Combining antidepressants is a recognised step for those failing to respond to monotherapy. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your Sequenced (stepped) treatment approaches are widely endorsed in the management of depression. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your To send this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. To send this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. Managing inadequate antidepressant response in depressive illness. Find out more about the Kindle Personal Document Service. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply. Then enter the ‘name’ part of your Kindle email address below. ‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi. The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Everyone in this study will receive aripiprazole and an antidepressant called a selective serotonin reuptake inhibitor (SSRI). Aripiprazole is an antipsychotic medication that has been approved by the Food and Drug Administration (FDA) for the treatment of schizophrenia. Listing a study does not mean it has been evaluated by the U. You will receive aripiprazole (Abilify) and one of the following SSRI antidepressant medications that will be determined by the study doctor and you: sertraline (Zoloft), citalapram (Celexa), or escitalopram (Lexapro). The purpose of the study is to assess the safety and effectiveness of the combination of aripiprazole (Abilify) and selective serotonin reuptake inhibitors (SSRIs) in subjects with psychotic major depression. The dose of aripiprazole (Abilify) will be 10 milligrams a day, and the starting doses for the SSRI anti-depressants will be: sertraline (Zoloft) 50 milligrams a day, citalopram (Celexa) 20 milligrams a day, and escitalopram (Lexapro) 10 milligrams a day. Matthews JD, Siefert C, Dording C, Denninger JW, Park L, van Nieuwenhuizen AO, Sklarsky K, Hilliker S, Homberger C, Rooney K, Fava M. An open study of aripiprazole and escitalopram for psychotic major depressive disorder.
Combination/augmentation strategies for improving the treatment of. some combinations and most augmenting strategies are often based on case. Bipolar Disorder Depression, Drug Sertraline Drug Lithium carbonate, Phase 3. and a Combination of Both Medications to Treat Symptoms of Bipolar Type II.