Notify all cases (suspected or confirmed) of pertussis to the Communicable Diseases Section, DHS, Victoria. • DHS information on pertussis • Notification info, and notification form Notes: Pertussis PCR testing: Send dry (non-charcoal or flocked swabs) from nasopharynx (preferably) or nose, or nasopharyngeal aspirate (NPA) Monday-Friday: specimens received in lab by 10am reported by 2pm. Saturday: Specimens received by 10am reported by 2pm. Antimicrobial agents given during the catarrhal phase may ameliorate the disease. Once cough is established, antimicrobial agents may not alter the course of the illness but are still recommended to limit the spread of disease. Pertussis-specific immunoglobulin is an investigational product that may be effective in decreasing paroxysms of cough, although it requires further evaluation. The Committee on Infectious Diseases (COID) of the American Academy of Pediatrics (Red Book Committee) currently recommends promptly treating all household and other close contacts (eg, children and staff at daycare centers) with erythromycin to limit secondary transmission. A 14-day course of oral erythromycin is the antimicrobial therapy of choice for patients with pertussis and for close contacts. Typical dosing schedule is 40-50 mg/kg/day (not to exceed 2 g/day) in 4 divided doses. Some experts prefer the estolate preparation in young infants because of more effective absorption, which may lead to decreased dosing and less frequent dosing intervals.
Erythromycin, clarithromycin Biaxin, and azithromycin Zithromax are preferred for the treatment of pertussis in persons one month and older. Dec 3, 2012. Azithromycin is now fully funded for all ages for pertussis treatment and. months old with whooping cough, around 70 will be hospitalised.