Prednisone is used for many different autoimmune diseases and inflammatory conditions, including: asthma, COPD, CIDP, rheumatic disorders, allergic disorders, ulcerative colitis and Crohn's disease, adrenocortical insufficiency, hypercalcemia due to cancer, thyroiditis, laryngitis, severe tuberculosis, urticaria (hives), lipid pneumonitis, pericarditis, multiple sclerosis, nephrotic syndrome, sarcoidosis, to relieve the effects of shingles, lupus, myasthenia gravis, poison oak exposure, Ménière's disease, autoimmune hepatitis, giant-cell arteritis, the Herxheimer reaction that is common during the treatment of syphilis, Duchenne muscular dystrophy, uveitis, and as part of a drug regimen to prevent rejection after organ transplant. It is important in the treatment of acute lymphoblastic leukemia, non-Hodgkin lymphomas, Hodgkin's lymphoma, multiple myeloma, and other hormone-sensitive tumors, in combination with other anticancer drugs. Prednisone can be used in the treatment of decompensated heart failure to increase renal responsiveness to diuretics, especially in heart failure patients with refractory diuretic resistance with large dose of loop diuretics. In terms of the mechanism of action for this purpose: prednisone, a glucocorticoid, can improve renal responsiveness to atrial natriuretic peptide by increasing the density of natriuretic peptide receptor type A in the renal inner medullary collecting duct, inducing a potent diuresis. Short-term side effects, as with all glucocorticoids, include high blood glucose levels (especially in patients with diabetes mellitus or on other medications that increase blood glucose, such as tacrolimus) and mineralocorticoid effects such as fluid retention. The mineralocorticoid effects of prednisone are minor, which is why it is not used in the management of adrenal insufficiency, unless a more potent mineralocorticoid is administered concomitantly. It can also cause depression or depressive symptoms and anxiety in some individuals. Prednisone is an anti-inflammatory that is used for all sorts of medical treatment programs involving a wide range of diseases, chronic pain afflictions, and other various disorders. Consequently, the dosages will vary and are often increased and decreased incrementally over the course of the treatment program. The common practice of prescribing physicians is to gradually lessen the dosage as the patient becomes no longer in need of the prednisone so as not to shock the body's system and cause further medical conditions to arise. The initial dosages for prednisone will vary from prednisone 5 mg to prednisone 60 mg, depending on the ailment or affliction for which it is prescribed. Some of the usual conditions include arthritis, Crohn's Disease, lupus, and severe allergic reactions of the skin. But because prednisone is a form of steroid, its uses are wide ranging, and therefore, its dosages follow suit accordingly. For example, prednisone is used as a maintenance therapy drug for Addison's Disease where adults might be required to ingest a very small amount of prednisone 5mg in the morning as well as in the evening before bed.
One of the dosage forms available for Prednisone is Injection Suspension. Wedgewood Pharmacy’s stringent quality control programs help ensure that our injection suspensions meet the specifications and high standards of the pharmacy industry.4 strengths of Prednisone Injection Suspension are available, ranging from 10 mg/ml to 50 mg/ml. Prednisone Injection Suspension Prescribed For: Dogs and Cats May be Prescribed For: Inflammation and Adrenal Insufficiency If you have any questions concerning these medications, please consult with your doctor. In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. US residents can call their local poison control center at 1-800-222-1222. Properly discard this product when it is expired or no longer needed.
Rheumatoid arthritis (RA) is a chronic inflammatory disease that makes the small joints of your hands and feet painful, swollen, and stiff. Without treatment, RA can lead to joint destruction and disability. Early diagnosis and treatment relieves symptoms and improves your quality of life with RA. Treatment plans usually include disease-modifying antirheumatic drugs (DMARDs) combined with nonsteroidal anti-inflammatory drugs (NSAIDs), and low-dose steroids. Alternative treatments are also available, including the use of the antibiotic minocycline. Let’s take a closer look at the role steroids play in treating RA. Steroids are technically called corticosteroids or glucocorticoids. They’re synthetic compounds similar to cortisol, a hormone your adrenal glands produce naturally. Until 20 years ago, steroids were the standard treatment for RA. Corticosteroids reduce the need for hospitalization in patients with croup and decrease morbidity and the incidence of respiratory failure in the treatment of patients with AIDS who havepneumonia. Dexamethasone is a long-acting, systemic corticosteroid; its potency is about 25 times greater than the short-acting products. Prednisone and methylprednisolone, which are intermediate-acting products, are four to five times more potent than hydrocortisone. H., Louisiana State University Medical Center, New Orleans, Louisiana DAWN CENDER, PHARM. Short-acting products such as hydrocortisone are the least potent. Chandler Medical Center, Lexington, Kentucky Am Fam Physician. Systemic corticosteroids have been used in the treatment of numerous medical conditions for approximately 50 years. Other often overlooked indications for corticosteroids are the treatment of hyperthyroid states, including thyroid storm, subacute thyroiditis and ophthalmopathy of Graves' disease. Systemic steroids can be used as adjuvant analgesics in the treatment of neuropathic and cancer-related pain.
Single-dose dexamethasone for mild-to-moderate asthma exacerbations. a larger dose of prednisone in. IM dexamethasone said they would prefer the IM injection. Oral administration of corticosteroids has been shown to have equivalent. Intramuscular dosage methylprednisolone acetate injection suspension, e.g.