Metformin is staggeringly cheap, it also happens to be an anti-aging agent with a high potential. Of course, tell your friends you are experimenting with a diabetic drug when you have no diabetes, and watch their face turn to horror at the idea that you would do anything to a sacred healthy body..how does Metformin work for anti-aging? (Stardust does not encourage experimentation with any pharmaceutical drugs without the supervision and guidance of qualified medical professionals). Well the results are not conclusive yet, but an ever-expanding group of scientists and their clinical trials are looking to validate Metformin as the first FDA approved anti-aging drug. There are also many potential pitfalls and downsides to Metformin that we will cover in this article. “I would consider this an early "hint" that Metformin may be more useful than just treating diabetes . Diabetes is a known cause of early aging and early death, and has been speculated that everyone develops diabetes eventually via aging, so being able to prevent or delay it is a BIG deal. It’s a really big plan that might one day change medicine and health care as we know it. Its promise: extending our years of healthy, disease-free living by decades. He is, after all, the director of the Institute for Aging Research at the Albert Einstein College of Medicine in the Bronx. And, as such, he usually talks about his plan with the caution of a seasoned researcher. Truth is, Barzilai is known among his colleagues for his excitability—one author says he could pass as the older brother of Austin Powers—and sometimes he can’t help himself. Like the time he referred to his plan—which, among other things, would demonstrate that human aging can be slowed with a cheap pill—as “history-making.” In 2015, he stood outside of the offices of the Food and Drug Administration, flanked by a number of distinguished researchers on aging, and likened the plan to a journey to “the promised land.”Last spring, Barzilai traveled to the Vatican to discuss the plan at a conference on cellular therapies. It was the second time he’d been invited to the conference, which is a pretty big deal in the medical world. At the last one, in 2013, he appeared alongside a dwarf from Ecuador, a member of a community of dwarfs whose near immunity to diabetes and cancer has attracted the keen interest of researchers. The 2016 conference featured a number of the world’s top cancer scientists and included addresses from Pope Francis and Joe Biden.
.pass_color_to_child_links a.u-margin-left--xs.u-margin-right--sm.u-padding-left--xs.u-padding-right--xs.u-absolute.u-absolute--center.u-width--100.u-flex-align-self--center.u-flex-justify--between.u-serif-font-main--regular.js-wf-loaded .u-serif-font-main--regular.amp-page .u-serif-font-main--regular.u-border-radius--ellipse.u-hover-bg--black-transparent.u-hover-bg--black-transparent:hover. Content Header .feed_item_answer_user.js-wf-loaded . Some people take Metformin not for the FDA approved reasons for prescribing the drug, rather as they believe it can probably have an impact in promoting general health and slow the aging process, it is probably the pharmaceutical most used for those purposes. Metformin has been listing in 1989 clinical trials, but only mentioned in 3 clinical trials on longevity: 1) The Metformin In Longevity Study; 2) Metformin and Longevity Genes In Pre-Diabetics; and 3) Metformin And Longevity. The Targeting Aging With Metformin is a clinical trial being sponsored by the American Federation of Aging Research which has been approved by the FDA. This will include 2 populations of subjects on of 1500 receiving metformin and another on placebo to investigate whether metformin delays onset of age related diseases ot precursor to conditions. Subjects will be in the age group of 70-80, residing within the USA who will be followed for 5 years. One 20 year old prospective study of metformin vs other conventional therapies for type 2 diabetes which included over 5,000 patients showed a 36% reduction in all cause mortality as compared to conventional therapy. However not all studies show such a dramatic effect.
The Life Extension Foundation explains it here " No one should take metformin without having a complete battery of blood tests to show their doctor that it is not. The more researchers learn about metformin, the more it seems like a. As one scientist recently put it to The New Yorker, the antiaging.